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Home - Products - Antibody Drug Conjugates (ADC) - ADCs Linker/Click Chemistry - Fmoc-8-amino-3,6-dioxaoctanoic acid

Fmoc-8-amino-3,6-dioxaoctanoic acid

CAS No. 166108-71-0

Fmoc-8-amino-3,6-dioxaoctanoic acid ( Fmoc-NH-PEG2-CH2COOH )

Catalog No. M23745 CAS No. 166108-71-0

Fmoc-8-amino-3,6-dioxaoctanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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1G 29 In Stock
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Biological Information

  • Product Name
    Fmoc-8-amino-3,6-dioxaoctanoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Fmoc-8-amino-3,6-dioxaoctanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • Description
    Fmoc-8-amino-3,6-dioxaoctanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Synonyms
    Fmoc-NH-PEG2-CH2COOH
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADC Linker;PROTAC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    166108-71-0
  • Formula Weight
    385.4
  • Molecular Formula
    C21H23NO6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O=C(O)COCCOCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nakamura A, et al. Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules. Biochemistry. 2020 Jan 21;59(2):205-211.
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